Drug design is a sophisticated pharmaceutical discipline with a rich history of achievements. Since the late 19th century, when Emil…
The process of drug discovery is an intricate, expensive, and time-consuming endeavor with a notably low success rate due to…
A minor functional modification to the structure of a drug candidate can have a profound impact on its biological profile.…
Nanomedicine, the field that encompasses the convergence of nanotechnology, pharmaceutical, and biomedical sciences, has experienced rapid advancements in recent years.…
Messenger RNA (mRNA) possesses extensive clinical potential for a range of therapeutic applications including vaccination, protein replacement, gene editing, immunotherapies,…
Kinases are enzymes that catalyze the transfer of a phosphate group from adenosine triphosphate (ATP), a high-energy phosphate-donating molecule, to…
Artificial intelligence (AI) is currently drawing increased attention in many aspects of science and technology. AI is the simulation of…
Targeted protein degradation (TPD) using small molecules termed as molecular glues (MGs) is potential to explore drug discovery and development…
Proteolysis targeting chimeric (PROTAC) technology is a recently discovered technique that has profound efficacy in cancer. This approach was first…
In recent years, many pharmaceutical companies have chosen to reduce their R&D investment in chemistry, viewing synthetic chemistry more as…