IUPAC Name
3-(dimethylamino)propane-1,2-diyl distearate
Synonyms
(18:0) DAP
CAS
121315-93-3
Chemical Formula
C41H81NO4
Molecular Weight
652.10
Formulation
Solid
SMILES
O=C(CCCCCCCCCCCCCCCCC)OC(CN(C)C)COC(CCCCCCCCCCCCCCCCC)=O
(18:0)-DAP is a cationic lipid featuring two saturated stearic acid (C18:0) chains. It is commonly used in the formulation of lipid nanoparticles (LNPs) designed for the encapsulation and delivery of messenger RNA (mRNA) and other nucleic acids. Its positive charge facilitates complexation with negatively charged mRNA, promoting efficient encapsulation and cellular uptake.
