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2,3-bis(icosanoyloxy)-N,N,N-trimethylpropan-1-aminium iodide

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  • IUPAC Name

    2,3-bis(icosanoyloxy)-N,N,N-trimethylpropan-1-aminium iodide

  • Chemical Formula

    C₄₆H₉₆INO₄

  • Molecular Weight

    902.2

  • Form

    Solid

  • SMILES

    O=C(CCCCCCCCCCCCCCCCCCC)OC(C[N+](C)(C)C)COC(CCCCCCCCCCCCCCCCCCC)=O.[I-]

2,3-bis(icosanoyloxy)-N,N,N-trimethylpropan-1-aminium iodide is a synthetic cationic lipid with two saturated C20 fatty acid tails and a trimethylammonium headgroup. It is structurally similar to DOTAP but with longer, saturated chains and iodide as the counterion, giving it a higher melting temperature, lower fluidity, and potentially enhanced stability in bilayer or nanoparticle formulations.

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