IUPAC Name
2,3-bis(dodecanoyloxy)-N-ethyl-N,N-dimethylpropan-1-aminium iodide
Chemical Formula
C₃₂H₆₆INO₄
Molecular Weight
675.8
Form
Solid
SMILES
O=C(OCC(C[N+](C)(CC)C)OC(CCCCCCCCCCC)=O)CCCCCCCCCCC.[I-]
Synonyms
1,2-Dilauroyl-3-(N,N-dimethyl-N-ethylammonium)propane iodide; DLEAP iodide
2,3-Bis(dodecanoyloxy)-N-ethyl-N,N-dimethylpropan-1-aminium iodide is a cationic amphiphilic lipid featuring two medium-chain saturated tails (C12:0) and a permanently charged quaternary ammonium headgroup with an ethyl substituent. It forms positively charged bilayers and vesicles, used in liposome formation, gene delivery, and model membrane studies. The ethyl substitution slightly increases hydrophobicity and influences bilayer fluidity and packing behavior compared to its trimethyl analogs.
