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Sodium 2,3-bis(oleoyloxy)propyl hydrogen phosphate

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  • IUPAC Name

    Sodium 2,3-bis(oleoyloxy)propyl hydrogen phosphate

  • Chemical Formula

    C₃₉H₇₃NaO₈P

  • Molecular Weight

    725

  • Form

    Solid

  • SMILES

    O=C(OCC(COP(O[H])([O-])=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)CCCCCCC/C=C\CCCCCCCC.[Na+]

Sodium 2,3-bis(oleoyloxy)propyl hydrogen phosphate is an anionic phospholipid analog — a synthetic phosphatidic acid–like molecule — often used in liposome formulations, membrane biophysics, and nanoparticle drug delivery systems. It closely mimics natural phospholipids such as phosphatidic acid but with a sodium counterion instead of a zwitterionic headgroup. It is used in anionic liposomes to adjust surface charge, membrane curvature, and encapsulation properties, helps mimic phosphatidic acid or phosphatidylglycerol in bilayer systems and is useful in studying membrane-protein interactions, fusion processes, and drug delivery mechanisms.

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