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3-((bis(benzyloxy)phosphoryl)oxy)propane-1,2-diyl didodecanoate

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  • IUPAC Name

    3-((bis(benzyloxy)phosphoryl)oxy)propane-1,2-diyl didodecanoate

  • Chemical Formula

    C₃₆H₆₃O₈P

  • Molecular Weight

    654

  • Form

    Solid

  • SMILES

    O=C(OCC(COP(OCC1=CC=CC=C1)(OCC2=CC=CC=C2)=O)OC(CCCCCCCCCCC)=O)CCCCCCCCCCC

  • AAPharmaSyn Stock ID

    00032

3-((Bis(benzyloxy)phosphoryl)oxy)propane-1,2-diyl didodecanoate is a synthetic phospholipid analog designed to mimic the structure and amphiphilic behavior of natural phosphatidylcholine-type lipids, but with benzyl-protected phosphate groups and medium-chain saturated fatty acid tails. It is used in the preparation of phospholipids such as phosphatidic acids, phosphatidylcholines, or phosphatidylethanolamines after deprotection of the phosphate group, enables the controlled synthesis of lipids with defined chain length and headgroup composition for biophysical membrane studies, is utilized in research on self-assembling amphiphiles and surface modification and serves as a hydrophobic phosphate reference compound in NMR and MS lipid analysis.

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