IUPAC Name
Sodium methyl (2,3-bis(tetradecanoyloxy)propyl)phosphonate
Chemical Formula
C₃₆H₇₂NaO₈P
Molecular Weight
703
Form
Solid
SMILES
O=C(OCC(CP(O[Na])(OC)=O)OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCCCC
AAPharmaSyn Stock ID
00033
Sodium methyl (2,3-bis(tetradecanoyloxy)propyl)phosphonate is a synthetic phospholipid analog that mimics the amphiphilic structure of natural phospholipids while replacing the typical phosphate diester headgroup with a phosphonate moiety. This subtle structural modification gives it enhanced chemical and enzymatic stability, making it valuable in liposome research, membrane models, and drug delivery formulations.
Because the molecule carries both hydrophobic fatty acid tails and a hydrophilic, anionic phosphonate headgroup (balanced by sodium), it behaves as a stable, anionic amphiphile in aqueous and lipid environments.
